ICUDDR, INL, ISSUP and NRC partnered to bring together the global in person and online event which took place in May 2022, in Abu Dhabi. The event showcased the latest learnings from the fields of substance use prevention, treatment and recovery support and allowed the global workforce to meet and exchange ideas. An in-person three-day conference was held at ADNEC, with keynote speakers sharing the latest developments from the field. A week-long online stream of sessions from the in-person conference, presentations with updates on the substance use situation and responses from around the world. Moreover, ISSUP Lebanon and Mentor Arabia members attended training and networking events and deepened professional relationships and important discussions on addiction policy, practice, and research.